Toxalim researchers are worried that Bisphenol S will leads to increased exposure to a hormonally active substance

A study conducted by the Gestation and Endocrine Disrupters team of Veterinary School of Toulouse and the Toxalim Research Unit (ENVT/Inra/Toulouse INP-PURPAN/UT3 Paul Sabatier), in collaboration with the Universities of Montreal and London, showed that bisphenol S (BPS) persist longer in the body.


Published in Environmental Health Perspectives, on July 17, 2019, the study shows that due to the estrogenic-mimetic properties of BPS comparable to those of BPA, the replacement of BPA by BPS leads to a multiplication by approximately 250 of the concentrations in the blood of a hormonally active substance. 

This result shows that exposure assessment is critical for the search for alternatives to substances of concern and could help to avoid regrettable substitution.


The restrictive measures governing the use of bisphenol A (BPA) in a large number of countries, including France, have led manufacturers to gradually replace bisphenol A with structural analogues, mainly bisphenol S (BPS).

The research conducted by the team in the piglet shows that the amount of ingested BPS that accesses the general bloodstream is about 100 times greater than that of BPA.


For more details, download the press release

Link to the article


6 allée Emile Monso - BP 34038
31029 Toulouse Cedex 4

+33 (0)5 34 32 30 00


  • Logo UTFTMP
  • Logo INP